发明申请
- 专利标题: MODIFIED PLANT VIRUS PARTICLES AND USES THEREFOR
- 专利标题(中): 改良植物病毒颗粒及其用途
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申请号: US13125482申请日: 2009-10-25
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公开(公告)号: US20120015899A1公开(公告)日: 2012-01-19
- 发明人: George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
- 申请人: George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
- 申请人地址: GB Norwich US MA Cambridge
- 专利权人: Plant Bioscience, Limited,Aura Biosciences
- 当前专利权人: Plant Bioscience, Limited,Aura Biosciences
- 当前专利权人地址: GB Norwich US MA Cambridge
- 国际申请: PCT/US09/05808 WO 20091025
- 主分类号: A61K31/7068
- IPC分类号: A61K31/7068 ; C12N1/19 ; C12N1/21 ; A61P35/00 ; C12N5/07
摘要:
Aspects of the invention provide modified virus-like particles that are designed for therapeutic applications. In particular, aspects of the invention provide CCMV coat proteins that are modified to generate virus-like particles, including mosaic virus-like particles, that can package and/or deliver one or more diagnostic and/or therapeutic agents. The invention also provides methods for treating subjects with one or more modified virus-like particles.
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