发明申请
US20120070871A1 POLYPEPTIDE HAVING D-LACTATE DEHYDROGENASE ACTIVITY, POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE, AND PROCESS FOR PRODUCTION OF D-LACTIC ACID
有权
具有D-脱水脱氢酶活性的多肽，编码多肽的多核苷酸以及D-乳酸的生产方法
- 专利标题： POLYPEPTIDE HAVING D-LACTATE DEHYDROGENASE ACTIVITY, POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE, AND PROCESS FOR PRODUCTION OF D-LACTIC ACID
- 专利标题（中）： 具有D-脱水脱氢酶活性的多肽，编码多肽的多核苷酸以及D-乳酸的生产方法
-
申请号： US13375882申请日： 2010-06-02
-
公开(公告)号： US20120070871A1公开(公告)日： 2012-03-22
- 发明人: Kenji Sawai , Kazumi Suda , Hideki Sawai , Katsushige Yamada , Junya Yamagishi
- 申请人： Kenji Sawai , Kazumi Suda , Hideki Sawai , Katsushige Yamada , Junya Yamagishi
- 申请人地址： JP Tokyo
- 专利权人： Toray Industries, Inc.
- 当前专利权人： Toray Industries, Inc.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2009-134213 20090603
- 国际申请： PCT/JP2010/059306 WO 20100602
- 主分类号： C12P7/56
- IPC分类号： C12P7/56 ; C12N1/19 ; C12N15/63 ; C12N9/04 ; C12N15/53
摘要：
Highly productive D-lactic acid fermentation uses a transformant obtained by introducing into a host cell a polynucleotide encoding a polypeptide according to any one of the following (A) to (C) in such a manner that the polypeptide is expressed, which polypeptide has a D-lactate dehydrogenase activity higher than those of conventional polypeptides: (A) a polypeptide having the amino acid sequence shown in SEQ ID NO:1 or 2; (B) a polypeptide having the same amino acid sequence as shown in SEQ ID NO:1 or 2 except that one or several amino acids are substituted, deleted, inserted and/or added, which polypeptide has a D-lactate dehydrogenase activity; and (C) a polypeptide having an amino acid sequence which has a sequence identity of not less than 80% to the amino acid sequence shown in SEQ ID NO:1 or 2, which polypeptide has a D-lactate dehydrogenase activity.
公开/授权文献
信息查询
