发明申请
- 专利标题: FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL CONTAINING SAME
- 专利标题(中): 熔融哌啶化合物和含有药物的化合物
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申请号: US13260711申请日: 2010-03-25
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公开(公告)号: US20120108581A1公开(公告)日: 2012-05-03
- 发明人: Masanori Ashikawa , Toshiharu Morimoto , Hajime Yamada , Shunji Takemura , Tatsuaki Nishiyama , Takeshi Doi , Hiroyuki Ishiwata
- 申请人: Masanori Ashikawa , Toshiharu Morimoto , Hajime Yamada , Shunji Takemura , Tatsuaki Nishiyama , Takeshi Doi , Hiroyuki Ishiwata
- 申请人地址: JP Aichi
- 专利权人: Kowa Company, Ltd
- 当前专利权人: Kowa Company, Ltd
- 当前专利权人地址: JP Aichi
- 优先权: JP2009-079544 20090327; JP2009-091484 20090403
- 国际申请: PCT/JP2010/055260 WO 20100325
- 主分类号: A61K31/473
- IPC分类号: A61K31/473 ; A61K31/4375 ; C12N5/02 ; C07D495/04 ; A61K31/4365 ; A61P7/06 ; A61K31/4745 ; C07D491/052 ; A61K31/4741 ; C07D491/056 ; C07D498/04 ; A61K31/5383 ; C07D471/04 ; C07D221/10
摘要:
The present invention provides a low molecular weight compound having EPO production-promoting action and/or hemoglobin production-promoting action. The present invention relates to a fused piperidine compound represented by the following general formula (1): (wherein, ring A represents a C10-14 aryl group or 5- to 10-membered heterocyclic group, X represents N—R7, a sulfur atom or an oxygen atom, R1, R2, R2′, R3 and R3′ independently represent a hydrogen atom, C1-6 alkyl group or C3-6 cycloalkyl group, and R4, R5 and R6 independently represent a hydrogen atom or halogen atom), or a salt thereof, or a solvate thereof.