发明申请
US20120148613A1 MULTIVALENT ENTRAIN-AND-AMPLIFY IMMUNOTHERAPEUTICS FOR CARCINOMA
审中-公开
多发性放射治疗和放大免疫球蛋白
- 专利标题: MULTIVALENT ENTRAIN-AND-AMPLIFY IMMUNOTHERAPEUTICS FOR CARCINOMA
- 专利标题(中): 多发性放射治疗和放大免疫球蛋白
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申请号: US13336523申请日: 2011-12-23
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公开(公告)号: US20120148613A1公开(公告)日: 2012-06-14
- 发明人: Adrian Ion Bot , Chih-Sheng Chiang , David C. Diamond , Jian Gong , Kent Andrew Smith , Liping Liu , Xiping Liu , Zhiyong Qiu
- 申请人: Adrian Ion Bot , Chih-Sheng Chiang , David C. Diamond , Jian Gong , Kent Andrew Smith , Liping Liu , Xiping Liu , Zhiyong Qiu
- 申请人地址: US CA Valencia
- 专利权人: MannKind Corporation
- 当前专利权人: MannKind Corporation
- 当前专利权人地址: US CA Valencia
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61P35/00
摘要:
The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.
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