发明申请
- 专利标题: NOVEL SULFONAMIDES AS L-CPT1 INHIBITORS
- 专利标题(中): 新型磺酰胺作为L-CPT1抑制剂
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申请号: US13477336申请日: 2012-05-22
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公开(公告)号: US20120232104A1公开(公告)日: 2012-09-13
- 发明人: Konrad Bleicher , Simona Maria Ceccarelli , Odile Chomienne , Patrizio Mattei , Tanja Schulz-Gasch , Christoph Martin Stahl
- 申请人: Konrad Bleicher , Simona Maria Ceccarelli , Odile Chomienne , Patrizio Mattei , Tanja Schulz-Gasch , Christoph Martin Stahl
- 优先权: EP05104904.7 20050606
- 主分类号: A61K31/196
- IPC分类号: A61K31/196 ; C07C311/29 ; A61K31/24 ; C07D413/04 ; A61K31/422 ; C07D409/04 ; A61K31/506 ; A61K31/4155 ; C07D213/79 ; C07D213/803 ; A61K31/44 ; C07C303/38 ; C07C303/40 ; C07D257/04 ; A61K31/41 ; C07D271/07 ; A61K31/4245 ; C07D291/04 ; A61P3/10 ; A61P3/08 ; A61P3/04 ; A61P9/12 ; A61P3/00 ; A61P3/06 ; A61P1/16 ; A61P9/10 ; A61P9/04 ; A61P13/12 ; C07C311/21
摘要:
The invention is concerned with novel sulfonamide derivatives of formula (I) wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.
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