发明申请
- 专利标题： ANTICALINS
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申请号： US13423666申请日： 2012-03-19
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公开(公告)号： US20120244596A1公开(公告)日： 2012-09-27
- 发明人: Arne Skerra , Gerald Beste , Frank Schmidt , Thomas Stibora
- 申请人： Arne Skerra , Gerald Beste , Frank Schmidt , Thomas Stibora
- 专利权人： Pieris AG
- 当前专利权人： Pieris AG
- 优先权： DE19742706.5 19970926
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; C07K16/00 ; C07K14/775 ; C07K19/00 ; C12N9/96
摘要：
The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. Alike immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.
公开/授权文献
- US08536307B2 Anticalins 公开/授权日：2013-09-17