Anticalins
    1.
    发明授权
    Anticalins 有权
    Anticalin

    公开(公告)号:US08536307B2

    公开(公告)日:2013-09-17

    申请号:US13423666

    申请日:2012-03-19

    IPC分类号: A61K38/00

    摘要: The invention relates to the production of novel proteins exhibiting binding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. Like immunoglobulin, the anticalin thus obtained can be used to identify or bind molecular structures.

    摘要翻译: 本发明涉及对某些配体表现出结合活性的新蛋白质的生产,即所谓的抗蛋白质。 为此,利用遗传工程方法,通过氨基酸置换在其天然配体结合口袋中修饰脂笼蛋白家族的肽结构。 像免疫球蛋白一样,如此得到的anticalin可用于鉴定或结合分子结构。

    Anticalins
    2.
    发明申请
    Anticalins 有权
    Anticalin

    公开(公告)号:US20100285564A1

    公开(公告)日:2010-11-11

    申请号:US12654809

    申请日:2010-01-05

    IPC分类号: C12N9/96 C07K14/00 C07K16/00

    摘要: The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. Alike immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

    摘要翻译: 本发明涉及对某些配体表现出结合活性的新蛋白质的生产,即所谓的抗蛋白质。 为此,脂笼蛋白家族的肽结构通过使用通用工程方法的天然配体结合口袋中的氨基酸替换来修饰。 如此获得的相似免疫球蛋白可以用于鉴定或结合分子结构。

    Anticalins
    5.
    发明授权
    Anticalins 有权
    Anticalin

    公开(公告)号:US08158753B2

    公开(公告)日:2012-04-17

    申请号:US12654809

    申请日:2010-01-05

    IPC分类号: A61K38/00

    摘要: The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. Alike immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

    摘要翻译: 本发明涉及对某些配体表现出结合活性的新蛋白质的生产,即所谓的抗蛋白质。 为此,脂笼蛋白家族的肽结构通过使用通用工程方法的天然配体结合口袋中的氨基酸替换来修饰。 如此获得的相似免疫球蛋白可以用于鉴定或结合分子结构。

    Anticalins
    6.
    发明申请
    Anticalins 有权
    Anticalin

    公开(公告)号:US20060058510A1

    公开(公告)日:2006-03-16

    申请号:US11224071

    申请日:2005-09-13

    IPC分类号: C07K14/775

    摘要: The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using generic engineering methods. Alike immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

    摘要翻译: 本发明涉及对某些配体表现出结合活性的新蛋白质的生产,即所谓的抗蛋白质。 为此,脂笼蛋白家族的肽结构通过使用通用工程方法的天然配体结合口袋中的氨基酸替换来修饰。 如此获得的相似免疫球蛋白可以用于鉴定或结合分子结构。

    Anticalins
    7.
    发明授权
    Anticalins 有权
    Anticalin

    公开(公告)号:US07250297B1

    公开(公告)日:2007-07-31

    申请号:US09509444

    申请日:1998-09-25

    IPC分类号: C12N15/01 G01N33/68

    摘要: The invention relates to the production of novel proteins exhibiting bonding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. A like immunoglobulin, the anticalin thus obtained can be used to identify or bond molecular structures.

    摘要翻译: 本发明涉及对某些配体表现出结合活性的新蛋白质的生产,即所谓的抗蛋白质。 为此,利用遗传工程方法,通过氨基酸置换在其天然配体结合口袋中修饰脂笼蛋白家族的肽结构。 类似的免疫球蛋白,所得到的anticalin可用于鉴定或结合分子结构。

    Receiver device, system, and method for low-energy reception of data
    8.
    发明授权
    Receiver device, system, and method for low-energy reception of data 有权
    用于低能量接收数据的接收机设备,系统和方法

    公开(公告)号:US09083580B2

    公开(公告)日:2015-07-14

    申请号:US13681135

    申请日:2012-11-19

    申请人: Frank Schmidt

    发明人: Frank Schmidt

    IPC分类号: H04B1/16 H04L27/06 H03D1/02

    CPC分类号: H04L27/06 H03D1/00 H03D1/02

    摘要: A receiver device, A system and a method for reception of a signal having an amplitude that has been modulated with information, wherein a resistive element is provided that converts an electrical quantity into a physical parameter.

    摘要翻译: 一种接收机装置,A系统和用于接收具有已经用信息调制的振幅的信号的方法,其中提供将电量转换成物理参数的电阻元件。

    Energy converter, counter with energy converter, system with counter, method for converting mechanical energy into electrical energy, and counting method
    9.
    发明授权
    Energy converter, counter with energy converter, system with counter, method for converting mechanical energy into electrical energy, and counting method 有权
    能量转换器,带能量转换器的计数器,带有计数器的系统,将机械能转换为电能的方法和计数方法

    公开(公告)号:US08531047B2

    公开(公告)日:2013-09-10

    申请号:US12667203

    申请日:2008-06-10

    IPC分类号: F02B63/04

    CPC分类号: F03G7/08

    摘要: An energy converter is disclosed which is provided for converting mechanical energy into electrical energy. Also disclosed is a counter, which includes its operating energy and also the counting information or the counting pulses from the energy converter named above. A method is also disclosed for converting mechanical energy into electrical energy. Also disclosed is a method for operating the counter with the electrical energy obtained according to the method. Also disclosed is a system made from at least one or more of the counters named above.

    摘要翻译: 公开了一种用于将机械能转换为电能的能量转换器。 还公开了一种计数器,其包括其操作能量以及来自上述能量转换器的计数信息或计数脉冲。 还公开了一种将机械能转换为电能的方法。 还公开了一种用根据该方法获得的电能来操作计数器的方法。 还公开了由至少一个或多个以上命名的计数器制成的系统。

    Electromagnetic energy transducer
    10.
    发明授权
    Electromagnetic energy transducer 有权
    电磁能传感器

    公开(公告)号:US08228151B2

    公开(公告)日:2012-07-24

    申请号:US13024141

    申请日:2011-02-09

    申请人: Frank Schmidt

    发明人: Frank Schmidt

    摘要: An electromagnetic energy transducer configured to convert mechanical energy into electrical energy comprises two magnetic elements including a permanent magnetic element and a soft-magnetic element and an electrical coil. The permanent magnetic element and the soft-magnetic element are arranged to form a magnetic circuit and one of the two magnetic elements is movable in relation to the other of the two magnetic elements. The electrical coil surrounds a part of the soft magnetic element. The movable magnetic element is held in a first position by a spring force and moved into a second position by applying an external mechanical force exceeding the spring force, and at the first position the magnetic flux within the soft magnetic element is different than the flux at the second position.

    摘要翻译: 构造成将机械能转换为电能的电磁能量转换器包括两个包括永磁元件和软磁元件和电线圈的磁性元件。 永磁元件和软磁元件被布置成形成磁路,并且两个磁性元件之一相对于两个磁性元件中的另一个可移动。 电线圈围绕软磁元件的一部分。 可移动磁性元件通过弹簧力保持在第一位置,并通过施加超过弹簧力的外部机械力而移动到第二位置,并且在第一位置,软磁元件内的磁通量不同于 第二个位置。