发明申请
- 专利标题： MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME
- 专利标题（中）： 大环化合物及其制备和使用方法
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申请号： US13525900申请日： 2012-06-18
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公开(公告)号： US20120252747A1公开(公告)日： 2012-10-04
- 发明人: Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
- 申请人： Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
- 主分类号： A61K31/7056
- IPC分类号： A61K31/7056 ; C07H17/08 ; A61P1/14 ; A61P31/00 ; A61P29/00 ; A61P35/00 ; C07H17/00 ; A61K31/706
摘要：
The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: or a pharmaceutically acceptable salt, ester, N-oxide, or prodrug thereof, wherein T, R1, R2, R3, D, E, F, and G are as defined herein. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory and prokinetic agents.