- 专利标题: COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS
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申请号: US13498491申请日: 2010-10-01
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公开(公告)号: US20120289522A1公开(公告)日: 2012-11-15
- 发明人: Thomas J. Seiders , Lucy Zhao , Jeannie Arruda , Bowei Wang , Brian Andrew Stearns , Yen Pham Truong , Jill Melissa Scott , John Howard Hutchinson , Ryan Clark , Heather Renee Coate , Nicholas Simon Stock , Deborah Volkots
- 申请人: Thomas J. Seiders , Lucy Zhao , Jeannie Arruda , Bowei Wang , Brian Andrew Stearns , Yen Pham Truong , Jill Melissa Scott , John Howard Hutchinson , Ryan Clark , Heather Renee Coate , Nicholas Simon Stock , Deborah Volkots
- 专利权人: Amira Pharmaceuticals INC.
- 当前专利权人: Amira Pharmaceuticals INC.
- 国际申请: PCT/US2010/051150 WO 20101001
- 主分类号: A61K31/42
- IPC分类号: A61K31/42 ; C07D261/08 ; C07D413/12 ; A61K31/4439 ; C07D417/12 ; A61P17/00 ; C07D495/04 ; A61K31/519 ; A61P11/00 ; A61P13/12 ; A61P1/16 ; C07D261/14 ; A61K31/428
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
公开/授权文献
- US09090573B2 Compounds as lysophosphatidic acid receptor antagonists 公开/授权日:2015-07-28
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