摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
摘要:
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
摘要:
Described herein are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
摘要:
In a wastewater treatment system, a clarifier has a submerged effluent launder, with a sloped, submerged plate that allows clarified liquid to exit through submerged openings. The sloped surface tends to accumulate solids, which can lead to algae growth. Typical internal scum collection system equipment prevents any efficient way to clear the accumulated sludge off the launder surface because of interferences. As disclosed here, a scum discharge area or box is placed external to the clarifier in one embodiment. Scum is wiped from a vertical surface of the launder assembly, above the sloped launder surface, and swept over a scum beach at one position in the clarifier, to drop into a lower trough and the flow out through the clarifier wall to a drop out box or scum discharge area. This allows for a rake-attached, sweeping launder wiper to be moved with the clarifier's rake to remove the accumulation of sludge from the launder's submerged surface, without elaborate moving parts. The sludge is swept back to settle in the clarifier, improving effluent quality by preventing sludge from exiting along with clarified water. In another embodiment the scum discharge box is internal, as a low-profile vertically disposed channel against the inside clarifier wall, leading to an existing scum pipe through the clarifier wall.
摘要:
A foundation haunch assembly used for attachment to a foundation wall and a method of making the haunch assembly using a concrete block machine. The haunch assembly includes a concrete haunch having an upper portion, a center portion and a lower portion. The upper portion of the haunch includes a flat top surface adapted for receiving a portion of a pre-cast concrete slab, stairs, stoops, poured in place concrete slab or other building structure thereon. Also, the upper portion includes an internal horizontal metal support rod along the length thereof. One end of the support rod is threaded to one end of a threaded coupling. The foundation haunch assembly also includes a variable length foundation bolt with a threaded end threaded into an opposite end of the threaded coupling. The foundation bolt is adapted for receipt through a hole in a portion of a vertical foundation wall. An opposite threaded end of the foundation bolt is attached to a nut. The nut is used for tightening and securing the foundation bolt and the concrete haunch to a side of the foundation wall.