发明申请
US20120295923A1 Aminocyclohexanes and Aminotetrahydropyrans and Related Compounds As Gamma-Secretase Modulators
审中-公开
氨基环己烷和氨基四氢吡喃和相关化合物作为γ分泌酶调节剂
- 专利标题: Aminocyclohexanes and Aminotetrahydropyrans and Related Compounds As Gamma-Secretase Modulators
- 专利标题(中): 氨基环己烷和氨基四氢吡喃和相关化合物作为γ分泌酶调节剂
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申请号: US13575370申请日: 2011-01-19
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公开(公告)号: US20120295923A1公开(公告)日: 2012-11-22
- 发明人: Christopher William Am Ende , Benjamin Adam Fish , Douglas Scott Johnson , Ricardo Lira , Christopher John O'Donnell , Martin Youngjin Pettersson , Corey Michael Stiff
- 申请人: Christopher William Am Ende , Benjamin Adam Fish , Douglas Scott Johnson , Ricardo Lira , Christopher John O'Donnell , Martin Youngjin Pettersson , Corey Michael Stiff
- 专利权人: PFIZER INC.
- 当前专利权人: PFIZER INC.
- 优先权: US61299811 20100129
- 国际申请: PCT/IB2011/050240 WO 20110119
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61K31/196 ; A61K31/421 ; C07D263/32 ; C07D309/14 ; A61K31/35 ; C07D239/26 ; C07D277/30 ; A61K31/426 ; A61K31/438 ; C07D221/20 ; C07D221/22 ; A61K31/439 ; A61K31/4433 ; C07D405/04 ; C07D213/55 ; A61K31/4418 ; A61P25/00 ; A61P25/18 ; C07C229/42
摘要:
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
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