发明申请
- 专利标题： AMINOPYRIMIDINES AS SYK INHIBITORS
- 专利标题（中）： 氨基嘧啶作为SYK抑制剂
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申请号： US13515941申请日： 2010-12-16
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公开(公告)号： US20120309735A1公开(公告)日： 2012-12-06
- 发明人: Michael D. Altman , Kenneth L. Arrington , Jason Burch , Bernard Cote , Jean-Francois Fournier , Jacques Yves Gauthier , Solomon Kattar , Sandra Lee Knowles , Jongwon Lim , Michelle R. Machacek , Alan B. Northrup , Michael H. Reutershan , Joel S. Robichaud , Adam J. Schell , Kerrie B. Spencer
- 申请人： Michael D. Altman , Kenneth L. Arrington , Jason Burch , Bernard Cote , Jean-Francois Fournier , Jacques Yves Gauthier , Solomon Kattar , Sandra Lee Knowles , Jongwon Lim , Michelle R. Machacek , Alan B. Northrup , Michael H. Reutershan , Joel S. Robichaud , Adam J. Schell , Kerrie B. Spencer
- 国际申请： PCT/US10/60703 WO 20101216
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; A61P19/02 ; A61K31/551 ; A61P11/06 ; A61P11/00 ; A61P29/00 ; C07D471/10 ; A61K31/5377
摘要：
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.
公开/授权文献
- US08735417B2 Aminopyrimidines as Syk inhibitors 公开/授权日：2014-05-27
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