发明申请
- 专利标题： Compositions for Improving Bone Mass
- 专利标题（中）： 改善骨质量的组合
-
申请号： US13571489申请日： 2012-08-10
-
公开(公告)号： US20130012445A1公开(公告)日： 2013-01-10
- 发明人: Xu Feng , Shunqing Wang
- 申请人： Xu Feng , Shunqing Wang
- 申请人地址： US AL Birmingham
- 专利权人： THE UAB RESEARCH FOUNDATION
- 当前专利权人： THE UAB RESEARCH FOUNDATION
- 当前专利权人地址： US AL Birmingham
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61P19/08 ; A61P19/02 ; A61P19/10 ; A61K38/07 ; A61P29/00
摘要：
The present invention provides a therapeutic composition, and method of use thereof, for improving bone mass, rigidity, or strength, or preventing and treating bone loss via modulation of the RANK signaling pathway. The therapeutic composition of the present invention comprises a RYBP peptide, or fragments thereof, that specifically interact with a motif of RANK to regulate osteoclastogenesis. The present invention further provides a composition, and method of use thereof, comprising a modulator that is capable of modulating the RYBP-RANK interaction, or modulating an effector in the RANK signaling pathway through the RYBP-RANK interaction.
公开/授权文献
- US08765908B2 Compositions for improving bone mass 公开/授权日：2014-07-01
信息查询
IPC分类:
