- 专利标题： GLUCOCORTICOID RECEPTOR ANTAGONISTS
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申请号： US13371834申请日： 2012-02-13
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公开(公告)号： US20130045972A1公开(公告)日： 2013-02-21
- 发明人: Jacques Bailly , Cornelia Hertel , Daniel Hunziker , Christian Lerner , Ulrike Obst Sander , Jens-Uwe Peters , Philippe Pflieger , Tanja Schulz-Gasch
- 申请人： Jacques Bailly , Cornelia Hertel , Daniel Hunziker , Christian Lerner , Ulrike Obst Sander , Jens-Uwe Peters , Philippe Pflieger , Tanja Schulz-Gasch
- 优先权： EP07117360.3 20070927
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; C07D241/12 ; C07D213/30 ; A61K31/505 ; A61P43/00 ; A61K31/498 ; C07D241/42 ; A61K31/5365 ; C07D498/04 ; C07D401/12 ; A61K31/4965 ; C07D239/26
摘要：
The present invention relates to compounds of formula I wherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
公开/授权文献
- US08883786B2 Glucocorticoid receptor antagonists 公开/授权日：2014-11-11
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