发明申请
- 专利标题: Chemical Compounds
- 专利标题(中): 化学化合物
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申请号: US13808653申请日: 2011-07-04
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公开(公告)号: US20130109708A1公开(公告)日: 2013-05-02
- 发明人: Alan Daniel Brown , David James Rawson , Robert Ian Storer , Nigel Alan Swain
- 申请人: Alan Daniel Brown , David James Rawson , Robert Ian Storer , Nigel Alan Swain
- 申请人地址: GB Sandwich, Kent
- 专利权人: Pfizer Limited
- 当前专利权人: Pfizer Limited
- 当前专利权人地址: GB Sandwich, Kent
- 国际申请: PCT/IB2011/052942 WO 20110704
- 主分类号: C07D213/69
- IPC分类号: C07D213/69 ; C07D213/30 ; C07D213/65 ; C07D471/04 ; A61K45/06 ; A61K31/472 ; C07D217/02 ; A61K31/505 ; C07D239/34 ; A61K31/44 ; A61K31/437
摘要:
The invention relates to sulfonamide derivatives, to their use in medicine, to 5 compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I):10 X NH O S O O R1 R2 R5 R4 R3 Het1 (I) or a pharmaceutically acceptable salt thereof, wherein X, Het1, R1, R2, R3, R4 and R5 are as defined in the description. 15 Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.
公开/授权文献
- US09102621B2 Acyl sulfonamide compounds 公开/授权日:2015-08-11
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