发明申请
US20130183252A1 COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME
审中-公开
化合物组合物中的抑制（块状）双酚A的化合物及其制备方法
- 专利标题： COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND METHODS OF MAKING SAME
- 专利标题（中）： 化合物组合物中的抑制（块状）双酚A的化合物及其制备方法
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申请号： US13370832申请日： 2012-02-10
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公开(公告)号： US20130183252A1公开(公告)日： 2013-07-18
- 发明人: Xiaodong LI , Andrew Patron , Catherine Tachdjian , Hong Xu , Qing Li , Alexey Pronin , Guy Servant , Lan Zhang , Thomas Brady , Vincent Darmohusodo , Melissa Arellano , Victor Selchau , Brett Weylan Ching , Donald S. Karanewsky , Paul Brust , Jing Ling , Wen Zhao , Chad Priest
- 申请人： Xiaodong LI , Andrew Patron , Catherine Tachdjian , Hong Xu , Qing Li , Alexey Pronin , Guy Servant , Lan Zhang , Thomas Brady , Vincent Darmohusodo , Melissa Arellano , Victor Selchau , Brett Weylan Ching , Donald S. Karanewsky , Paul Brust , Jing Ling , Wen Zhao , Chad Priest
- 申请人地址： US CA San Diego
- 专利权人： Senomyx, Inc.
- 当前专利权人： Senomyx, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： C07C311/17
- IPC分类号： C07C311/17 ; C07D223/18 ; A61K8/46 ; A61Q11/00 ; C07D213/71 ; C07D333/34 ; C07D317/58 ; A61K8/49 ; C07C311/16 ; C07C311/19 ; C07C311/46 ; C07C311/18 ; C07C233/73 ; C07D333/20 ; C07D213/42 ; C07D217/08 ; A23L1/22 ; C07D307/52
摘要：
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.
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