发明申请
- 专利标题： ADHESION SIGNATURES
- 专利标题（中）： 粘合标志
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申请号： US13794772申请日： 2013-03-11
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公开(公告)号： US20130274124A1公开(公告)日： 2013-10-17
- 发明人: Sangeeta N. Bhatia , David Fernandes Braga Malta , Nathan Edward Reticker-Flynn , Gregory H. Underhill , Robert Edward Schwartz
- 申请人： Sangeeta N. Bhatia , David Fernandes Braga Malta , Nathan Edward Reticker-Flynn , Gregory H. Underhill , Robert Edward Schwartz
- 申请人地址： US MA Cambridge
- 专利权人： Massachusetts Institute of Technology
- 当前专利权人： Massachusetts Institute of Technology
- 当前专利权人地址： US MA Cambridge
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; C12N5/0735 ; C12N5/09 ; G01N33/68 ; C12N5/071
摘要：
The present invention provides arrays comprising polypeptides associated with extracellular matrix that can be used to isolate, differentiate, or culture certain cell types including stem cells, cancer cells, and/or primary hepatocytes. The array comprises at least a pair of polypeptides that comprise a polypeptide associated with extracellular matrix or functional fragments thereof. The invention also provides for methods of diagnosing and/or prognosing a certain disease or disorder through contacting a cell sample from a patient with an array comprising at least a pair of polypeptides that comprise a polypeptide sequence associated with extracellular matrix or functional fragments thereof.