发明申请
- 专利标题： HETEROCYCLIC-SUBSTITUTED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
- 专利标题（中）： 杂环取代的苯唑嘌呤衍生物及其用于治疗病毒性疾病的方法
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申请号： US14343448申请日： 2012-08-16
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公开(公告)号： US20140199263A1公开(公告)日： 2014-07-17
- 发明人: Casey Cameron McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Zhong Lai , Qun Dang , Nicolas Zorn
- 申请人： Casey Cameron McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Zhong Lai , Qun Dang , Nicolas Zorn
- 优先权： CNPCT/CN2011/079467 20110908
- 国际申请： PCT/CN2012/080214 WO 20120816
- 主分类号： C07D513/04
- IPC分类号： C07D513/04 ; A61K31/497 ; C07D405/14 ; A61K31/4439 ; C07D413/14 ; A61K31/4245 ; A61K31/444 ; A61K31/506 ; C07D498/04 ; C07D417/14 ; A61K31/5377 ; A61K31/501 ; A61K31/433 ; C07D409/14 ; A61K31/5365 ; A61K31/5383 ; C07F7/10 ; A61K31/695 ; A61K45/06 ; C07D471/04
摘要：
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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