发明申请
US20140242651A1 ENZYMATICALLY CATALYZED METHOD OF PREPARING MONO-ACYLATED POLYOLS
审中-公开
制备单取代多元醇的酶催化方法
- 专利标题： ENZYMATICALLY CATALYZED METHOD OF PREPARING MONO-ACYLATED POLYOLS
- 专利标题（中）： 制备单取代多元醇的酶催化方法
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申请号： US14220301申请日： 2014-03-20
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公开(公告)号： US20140242651A1公开(公告)日： 2014-08-28
- 发明人: Bernhard Hauer , Cecilia Kvarnström Branneby , Karl Hult , Anders Magnusson , Anders Hamberg
- 申请人： Bernhard Hauer , Cecilia Kvarnström Branneby , Karl Hult , Anders Magnusson , Anders Hamberg
- 申请人地址： DE Ludwigshafen
- 专利权人： BASF SE
- 当前专利权人： BASF SE
- 当前专利权人地址： DE Ludwigshafen
- 优先权： EP09170458.5 20090916
- 主分类号： C12P7/62
- IPC分类号： C12P7/62 ; C12N9/20
摘要：
The present invention relates to a biocatalytic method of preparing a mono-acylated polyol catalyzed by triacylglycerol lipase mutants, as for example derived from Candida antarctica lipase B (CALB); a biocatalytic method of enantioselectively preparing an asymmetric mono-acylated polyol, catalyzed by the same enzyme mutants; as well as the use of a mutated triacylglycerol lipase in a method of preparing mono-acylated polyols. The invention also provides novel mutants, coding sequences thereof, and recombinant microorganisms carrying said coding sequences.
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