发明申请
US20150230918A1 BIOMATERIAL BASED ON ALIGNED FIBERS, ARRANGED IN A GRADIENT INTERFACE, WITH MECHANICAL REINFORCEMENT FOR TRACHEAL REGENERATION AND REPAIR
审中-公开
基于对准纤维的生物材料，安装在梯度界面，机械加固用于河道再生和修复
- 专利标题： BIOMATERIAL BASED ON ALIGNED FIBERS, ARRANGED IN A GRADIENT INTERFACE, WITH MECHANICAL REINFORCEMENT FOR TRACHEAL REGENERATION AND REPAIR
- 专利标题（中）： 基于对准纤维的生物材料，安装在梯度界面，机械加固用于河道再生和修复
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申请号： US14239049申请日： 2012-08-15
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公开(公告)号： US20150230918A1公开(公告)日： 2015-08-20
- 发明人: Michael Detamore , Lindsey Ott , Robert Weatherly
- 申请人： Michael Detamore , Lindsey Ott , Robert Weatherly
- 申请人地址： US KS Lawrence
- 专利权人： THE UNIVERSITY OF KANSAS
- 当前专利权人： THE UNIVERSITY OF KANSAS
- 当前专利权人地址： US KS Lawrence
- 国际申请： PCT/US2012/050974 WO 20120815
- 主分类号： A61F2/20
- IPC分类号： A61F2/20 ; A61L27/10 ; A61L27/14
摘要：
An implant can include a plurality of polymeric fibers associated together into a fibrous body. The fibrous body is capable of being shaped to fit a tracheal defect and capable of being secured in place by suture or by bioadhesive. The fibrous body can have aligned fibers (e.g., circumferentially aligned) or unaligned fibers. The fibrous body can be electrospun. The fibrous body can have a first characteristic in a first gradient distribution across at least a portion of the fibrous body. The fibrous body can include one or more structural reinforcing members, such as ribbon structural reinforcing members, which can be embedded in the plurality of fibers. The fibrous body can include one or more structural reinforcing members bonded to the fibers with liquid polymer as an adhesive, the liquid polymer having a substantially similar composition of the fibers.
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