公开(公告)号：US20150230918A1

公开(公告)日：2015-08-20

申请号：US14239049

申请日：2012-08-15

申请人： Michael Detamore ,  Lindsey Ott ,  Robert Weatherly

发明人： Michael Detamore ,  Lindsey Ott ,  Robert Weatherly

IPC分类号： A61F2/20 ,  A61L27/10 ,  A61L27/14

CPC分类号： A61F2/20 ,  A61F2/04 ,  A61F2002/046 ,  A61F2210/0076 ,  A61F2250/0018 ,  A61F2250/0028 ,  A61L27/10 ,  A61L27/14 ,  A61L27/18 ,  A61L27/34 ,  A61L2300/414 ,  A61L2420/04 ,  A61L2420/08 ,  A61L2430/22 ,  C08L67/04

摘要： An implant can include a plurality of polymeric fibers associated together into a fibrous body. The fibrous body is capable of being shaped to fit a tracheal defect and capable of being secured in place by suture or by bioadhesive. The fibrous body can have aligned fibers (e.g., circumferentially aligned) or unaligned fibers. The fibrous body can be electrospun. The fibrous body can have a first characteristic in a first gradient distribution across at least a portion of the fibrous body. The fibrous body can include one or more structural reinforcing members, such as ribbon structural reinforcing members, which can be embedded in the plurality of fibers. The fibrous body can include one or more structural reinforcing members bonded to the fibers with liquid polymer as an adhesive, the liquid polymer having a substantially similar composition of the fibers.

摘要翻译： 植入物可以包括与纤维体相关联的多个聚合物纤维。 纤维体能够成形为适合气管缺损并且能够通过缝线或通过生物粘附固定在适当位置。 纤维体可以具有对准的纤维（例如，周向排列）或未对准的纤维。 纤维体可以电纺丝。 纤维体可以具有穿过纤维体的至少一部分的第一梯度分布的第一特征。 纤维体可以包括一个或多个可以嵌入多根纤维中的结构加强构件，例如带状结构增强构件。 纤维体可以包括一个或多个结合的增强部件，其结合到具有液体聚合物作为粘合剂的纤维上，该液体聚合物具有基本相似的纤维组成。