The present invention relates to skin care compositions containing a small peptide mimic of TGF-β and to methods of using such compositions to manage the health and condition of skin and scalp. More preferably, the skin care compositions contain a safe and effective amount of a peptide mimic for TGF-β, derivatives of a peptide mimic for TGF-β, and mixtures thereof; a safe and effective amount of at least one skin care active; and a dermatologically acceptable carrier.