Invention Application
- Patent Title: Potent and Efficient Cytotoxic Peptides and Antibody-Drug Conjugates thereof and Their Synthesis
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Application No.: US15044043Application Date: 2016-02-15
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Publication No.: US20160158307A1Publication Date: 2016-06-09
- Inventor: Shanghui Hu , Lucy Xiumin Zhao , Jinying Ning , Xufang Tian , Chao Li , Wei Hu , Xu Liu , Bonnie Y. Hu
- Applicant: Shanghui Hu , Lucy Xiumin Zhao , Jinying Ning , Xufang Tian , Chao Li , Wei Hu , Xu Liu , Bonnie Y. Hu
- Applicant Address: US NJ Princeton
- Assignee: ACES Pharma Inc.
- Current Assignee: ACES Pharma Inc.
- Current Assignee Address: US NJ Princeton
- Main IPC: A61K38/05
- IPC: A61K38/05 ; C07K5/062 ; A61K47/48 ; C07K16/28 ; C07K16/32
Abstract:
The present invention provides a family of novel cytotoxic pentapeptides, which show potent antitumor activities against several cancer lines. The antibody-drug conjugates prepared from those pentapeptides can efficiently kill cancer cells.
Information query
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