发明申请
- 专利标题： DESIGNER OSTEOGENIC PROTEINS
- 专利标题（中）： 设计者蛋白质蛋白
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申请号： US14589468申请日： 2015-01-05
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公开(公告)号： US20160207973A1公开(公告)日： 2016-07-21
- 发明人: Stephen BERASI , Robert Vincent Martinez , Michael John Cain , John Martin Wozney , Howard Joel Seeherman , Zong Sean Juo , Valerie Perrine Calabro , Christopher Todd Brown
- 申请人： Stephen BERASI , Robert Vincent Martinez , Michael John Cain , John Martin Wozney , Howard Joel Seeherman , Zong Sean Juo , Valerie Perrine Calabro , Christopher Todd Brown
- 主分类号： C07K14/51
- IPC分类号： C07K14/51
摘要：
The invention relates to novel designer osteogenic proteins having altered affinity for a cognate receptor, nucleic acids encoding the same, and methods of use therefor. More preferably, the novel designer osteogenic proteins are designer BMPs and have altered affinity for a cognate BMP receptor. The designer BMPs demonstrate altered biological characteristics and provide potential useful novel therapeutics.
公开/授权文献
- US09688735B2 Designer osteogenic proteins 公开/授权日：2017-06-27
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