发明申请
US20160326553A1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES
审中-公开
具有增加碳通量效率的方法和有机体
- 专利标题： METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES
- 专利标题（中）： 具有增加碳通量效率的方法和有机体
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申请号： US15108259申请日： 2014-12-23
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公开(公告)号： US20160326553A1公开(公告)日： 2016-11-10
- 发明人: Anthony P. BURGARD , Robin E. OSTERHOUT , Stephen J. VAN DIEN , Priti PHARKYA , Tae Hoon YANG , Jungik CHOI
- 申请人： GENOMATICA, INC.
- 申请人地址： US CA San Diego
- 专利权人： GENOMATICA, INC.
- 当前专利权人： GENOMATICA, INC.
- 当前专利权人地址： US CA San Diego
- 国际申请： PCT/US14/72178 WO 20141223
- 主分类号： C12P7/18
- IPC分类号： C12P7/18 ; C12N9/02 ; C12N15/52 ; C12N9/52 ; C12N9/88 ; C12N9/16 ; C12N9/12
摘要：
The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at least a second attenuation of a succinyl-CoA converting enzyme or a gene encoding a succinate producing enzyme within a multi-step pathway having a net conversion of succinyl-CoA to succinate.
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