Invention Application
- Patent Title: CYTOTOXIC ANTIBODY
- Patent Title (中): CYTOTOXIC抗体
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Application No.: US15101586Application Date: 2014-12-02
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Publication No.: US20170002331A1Publication Date: 2017-01-05
- Inventor: Boon Hwa Andre Choo , Jiyun Zheng
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Priority: SG201308964-4 20131203
- International Application: PCT/SG2014/000570 WO 20141202
- Main IPC: C12N5/16
- IPC: C12N5/16 ; C12N5/00 ; C07K16/18

Abstract:
An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAc1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
Public/Granted literature
- US10428312B2 Cytotoxic antibody Public/Granted day:2019-10-01
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