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公开(公告)号:US20170002331A1
公开(公告)日:2017-01-05
申请号:US15101586
申请日:2014-12-02
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor: Boon Hwa Andre Choo , Jiyun Zheng
CPC classification number: C12N5/163 , C07K16/18 , C07K16/44 , C07K2317/35 , C07K2317/565 , C07K2317/73 , C12N5/0081
Abstract: An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAc1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
Abstract translation: 公开了结合糖基化蛋白质的抗体,其中糖基化包括聚糖基序Fucα1-2Galβ1-3GlcNAc1-3Galβ1或Fucα1-2Galβ1-3GlcNAc。 还公开了对未分化多能细胞具有细胞毒性的抗体。
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公开(公告)号:US11512292B2
公开(公告)日:2022-11-29
申请号:US16545736
申请日:2019-08-20
Applicant: Agency for Science, Technology and Research
Inventor: Boon Hwa Andre Choo , Jiyun Zheng
Abstract: An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAcβ1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
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公开(公告)号:US10428312B2
公开(公告)日:2019-10-01
申请号:US15101586
申请日:2014-12-02
Applicant: Agency for Science, Technology and Research
Inventor: Boon Hwa Andre Choo , Jiyun Zheng
Abstract: An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAc1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
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