Invention Application
US20170016043A1 SYSTEM AND METHOD FOR IMPROVED TRANSIENT PROTEIN EXPRESSION IN CHO CELLS
审中-公开
用于在CHO细胞中改进的瞬时蛋白表达的系统和方法
- Patent Title: SYSTEM AND METHOD FOR IMPROVED TRANSIENT PROTEIN EXPRESSION IN CHO CELLS
- Patent Title (中): 用于在CHO细胞中改进的瞬时蛋白表达的系统和方法
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Application No.: US15209695Application Date: 2016-07-13
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Publication No.: US20170016043A1Publication Date: 2017-01-19
- Inventor: Jonathan ZMUDA , Chao Yan LIU
- Applicant: LIFE TECHNOLOGIES CORPORATION
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C07K14/505 ; C07K16/00

Abstract:
The present invention is directed generally to systems and methods suitable for high level expression of recombinant proteins in suspension CHO cells. In particular, the invention allows introduction of the invention obviates the need to replace, replenish or supplement the growth medium during the procedure. The invention also relates to compositions and kits useful for culturing and transforming/transfecting suspension CHO cells.
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