In a first aspect, the present disclosure provides a method of forming a semiconductor device, including providing an SOI structure comprising a base substrate, a buried insulating material layer formed on the base substrate and an active semiconductor layer formed on the buried insulating structure, forming a germanium-comprising layer on an exposed surface of the active semiconductor layer, forming a trench isolation structure, the trench isolation structure extending through the germanium-comprising layer and the active semiconductor layer, performing an annealing process after the trench isolation structure is formed, the annealing process resulting in an oxide layer disposed on a germanium-comprising active layer which is formed on the buried insulating material layer, and removing the oxide layer for exposing an upper surface of the germanium-comprising active layer.