Invention Application
- Patent Title: ALKYNYL ALCOHOLS AND METHODS OF USE
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Application No.: US15425698Application Date: 2017-02-06
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Publication No.: US20170145034A1Publication Date: 2017-05-25
- Inventor: Nicole Blaquiere , Georgette Castanedo , Jianwen A. Feng , Baihua Hu , Steven Staben , Po-wai Yuen , Guosheng Wu , Jason Burch
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Priority: CNPCT/CN2013/000993 20130822; CNPCT/CN2014/078680 20140528; CNPCT/CN2014/082687 20140722
- Main IPC: C07D513/04
- IPC: C07D513/04 ; C07D401/14 ; C07D491/052 ; C07D471/04 ; C07D413/10 ; C07D491/048 ; C07D403/14 ; C07D413/14 ; C07D495/04 ; C07D487/04 ; C07D417/10 ; C07D403/10 ; C07D401/10
Abstract:
The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
Information query
