- 专利标题: METHOD FOR SCREENING DRUG-SACCHARIDE CONJUGATES
-
申请号: US15595115申请日: 2017-05-15
-
公开(公告)号: US20170248580A1公开(公告)日: 2017-08-31
- 发明人: Yingjun Mu , Ruojing Yang , Xinghai Li , Margaret Wu , Qing Dallas-yang , Yuli Chen , Ge Dai , Songnian Lin , David E. Kelley , Mark Erion
- 申请人: Merck Sharp & Dohme Corp.
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 主分类号: G01N33/50
- IPC分类号: G01N33/50 ; G01N33/569
摘要:
Methods for identifying drug-saccharide conjugates that bind the mannose receptor, C type 1, (MRC1) and may be taken up by cells expressing MRC1, and the use of such drug-saccharide conjugates for treatment of particular diseases are described. In particular, the methods for identifying insulin-saccharide conjugates that bind the MRC1 receptor and may be taken up by cells expressing the MRC1 and use of such conjugates for treatment of diabetes are described.
信息查询
IPC分类: