发明申请
- 专利标题: ALPHA-AMINOAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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申请号: US15516395申请日: 2015-09-24
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公开(公告)号: US20170298011A1公开(公告)日: 2017-10-19
- 发明人: Ki Duk PARK , ChangJoon Justin LEE , Dong Jin KIM , Ae Nim PAE , Hyun Ah CHOO , Sun Joon MIN , Yong Koo KANG , Yun Kyung KIM , Hyo Jung SONG , Ji Won CHOI , Min Ho NAM , Jun Young HEO , Seul Ki YEON , Bo Ko JANG , Eun Ji JU , Seon Mi JO , Jong-Hyun PARK
- 申请人: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 优先权: KR10-2014-0132983 20141002; KR10-2015-0132281 20150918
- 国际申请: PCT/KR2015/010104 WO 20150924
- 主分类号: C07C237/06
- IPC分类号: C07C237/06 ; C07C231/12
摘要:
The present disclosure relates to an α-aminoamide derivative compound and a pharmaceutical composition containing the same. According to various embodiments of the present disclosure, provided is a therapeutic agent which can overcome the disadvantages of existing drugs used as a MAO-B inhibitor and, specifically, reversibly inhibits MAO-B through a non-covalent bond so as to alleviate or eliminate the side effects of the existing drugs which exhibit a therapeutic effect by irreversibly acting via a covalent bond with MAO-B. Particularly, a new compound having superior stability and efficacy compared to the existing reversible MAO-B inhibitors may be provided.
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