Invention Application
- Patent Title: ANIMAL MODEL FOR NEPHROPATHY AND AGENTS FOR TREATING THE SAME
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Application No.: US15591669Application Date: 2017-05-10
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Publication No.: US20170339928A1Publication Date: 2017-11-30
- Inventor: Deanna Grant Wilson , Oded Foreman , Andrew Peterson , Xiaohui Wen , Suzanna J. Scales
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: A01K67/027
- IPC: A01K67/027 ; A61K49/00 ; C12N15/85 ; C07K16/00
Abstract:
A non-human transgenic animal expressing ApoL1 is provided as well as a method for generating the same. Also provided is a method for identifying an agent capable of reducing the progression of an ApoL1 mediated nephropathy. Furthermore, an isolated antibody is provided which binds to the human variants of ApoL1.
Information query
