Invention Application
- Patent Title: INHIBITION AND DIAGNOSTICS OF EMERGING TETRACYCLINE RESISTANCE ENZYMES
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Application No.: US15633254Application Date: 2017-06-26
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Publication No.: US20170369864A1Publication Date: 2017-12-28
- Inventor: Niraj Tolia , Gautam Dantas , Timothy Wencewicz , Jooyoung Park , Andrew Gasparrini , Kevin Forsberg , Joseph Vogel , Margaret Ruth Reck , Chanez Tiffany Symister , Jana L. Markley
- Applicant: Niraj Tolia , Gautam Dantas , Timothy Wencewicz , Jooyoung Park , Andrew Gasparrini , Kevin Forsberg , Joseph Vogel , Margaret Ruth Reck , Chanez Tiffany Symister , Jana L. Markley
- Applicant Address: US MO St. Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO St. Louis
- Main IPC: C12N9/99
- IPC: C12N9/99 ; C12Q1/04 ; A61K39/40 ; A61K38/00 ; A61K31/65 ; A61K47/00 ; C12N9/00
Abstract:
The present disclosure provides compositions and methods for treating bacterial infections in a subject. The methods comprise administering a compound that binds a FAD-dependent flavoenzyme and a tetracycline, analog, derivative, or pharmaceutically acceptable salt thereof.
Public/Granted literature
- US10273468B2 Inhibition and diagnostics of emerging tetracycline resistance enzymes Public/Granted day:2019-04-30
Information query
