In some examples, a system includes an article of personal protective equipment (PPE) comprising one or more sensors, the one or more sensors configured to generate usage data that is indicative of an operation of the article of PPE; and at least one computing device comprising a memory and one or more computer processors that: receive the usage data that is indicative of the operation of the article of PPE; apply the usage data to a safety learning model that predicts a likelihood of an occurrence of a safety event associated with the article of PPE based at least in part on previously generated usage data that corresponds to the safety event; and perform, based at least in part on predicting the likelihood of the occurrence of the safety event, at least one operation.