Invention Application
- Patent Title: CYTOMEGALOVIRUS ANTIGENS
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Application No.: US15533483Application Date: 2015-12-07
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Publication No.: US20180265551A1Publication Date: 2018-09-20
- Inventor: Andrea CARFI , Sumana CHANDRAMOULI , Ethan C. SETTEMBRE
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE Rixensart
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE Rixensart
- Priority: EP14196854.5 20141208
- International Application: PCT/IB2015/059420 WO 20151207
- Main IPC: C07K14/005
- IPC: C07K14/005
Abstract:
The invention generally relates to recombinant human cytomegalovirus (CMV) gB proteins and immunogenic fragments thereof, which do not comprise a transmembrane (TM) domain; and comprise one or more mutations that reduce the aggregation between the monomeric trimers of gB, and/or adhesion of the monomeric trimer of gB to the host cell.
Public/Granted literature
- US10364273B2 Cytomegalovirus antigens Public/Granted day:2019-07-30
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