Invention Application
- Patent Title: MULTI-LAYER AIRWAY ORGANOIDS AND METHODS OF MAKING AND USING THE SAME
-
Application No.: US15768100Application Date: 2016-10-14
-
Publication No.: US20180291350A1Publication Date: 2018-10-11
- Inventor: Sean V. Murphy , Anthony Atala
- Applicant: Wake Forest University Health Sciences
- International Application: PCT/US16/56947 WO 20161014
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12M3/00 ; C12M3/06 ; C12M1/00 ; C12N1/20
Abstract:
Provided herein are artificial lung organoids. The artificial lung organoids may include an epithelial cell layer comprising mammalian lung epithelial cells, a stromal cell layer comprising mammalian lung fibroblast cells and an endothelial cell layer comprising mammalian endothelial cells. The artificial lung organoids may optionally include a porous membrane between said epithelial cell layer and said stromal cell layer and/or between said stromal cell layer and said endothelial lung cell layer.
Public/Granted literature
- US11001811B2 Multi-layer airway organoids and methods of making and using the same Public/Granted day:2021-05-11
Information query
