- 专利标题： LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS
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申请号： US16115883申请日： 2018-08-29
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公开(公告)号： US20180369386A1公开(公告)日： 2018-12-27
- 发明人: Jeremy Lee Baryza , Rohan Eric John Beckwith , Keith Bowman , Crystal Byers , Tanzina Fazal , Gabriel Grant Gamber , Cameron Chuck-Munn Lee , Ritesh Bhanudasji Tichkule , Chandra Vargeese , Shuangxi Wang , Laura West , Thomas Zabawa , Junping Zhao
- 申请人： Novartis AG
- 主分类号： A61K47/18
- IPC分类号： A61K47/18 ; C07C229/14 ; A61K9/127 ; A61K9/51 ; C12N15/113 ; C07D317/28 ; C07D295/096 ; C07D213/79 ; C07D213/69 ; C07D205/04 ; C07C235/42 ; A61K9/00 ; C07C229/12 ; C07C219/06 ; C07C217/58 ; A61K47/22 ; A61K38/22 ; A61K31/713 ; A61K48/00
摘要：
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
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