Invention Application
- Patent Title: ENHANCED THERMAL STABILITY FOR ADENOVIRAL VECTORS THROUGH SPRAY DRYING
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Application No.: US15757033Application Date: 2016-09-02
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Publication No.: US20190062692A1Publication Date: 2019-02-28
- Inventor: Michael Thompson , Zhou Xing , Daniel Adam LeClair , Emily Cranston
- Applicant: MCMASTER UNIVERSITY
- Applicant Address: CA ON Hamilton
- Assignee: MCMASTER UNIVERSITY
- Current Assignee: MCMASTER UNIVERSITY
- Current Assignee Address: CA ON Hamilton
- International Application: PCT/CA2016/051046 WO 20160902
- Main IPC: C12N1/04
- IPC: C12N1/04 ; C12N15/86 ; A61K9/00 ; A61K39/235 ; A61K9/16
Abstract:
The present application includes stabilized adenovirus compositions comprising an adenovirus and an excipient, wherein the excipient comprises a mixture of dextran and mannitol in amounts effective to maintain at least 40% of the adenovirus activity after spray drying.
Public/Granted literature
- US10752876B2 Enhanced thermal stability for adenoviral vectors through spray drying Public/Granted day:2020-08-25
Information query
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