- 专利标题： NAPHTHOQUINONES, PRO-DRUGS, AND METHODS OF USE THEREOF
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申请号： US16063347申请日： 2016-12-16
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公开(公告)号： US20190071380A1公开(公告)日： 2019-03-07
- 发明人: Jinming GAO , Yuliang LIU , Qi WEI , Xinpeng MA , Gang HUANG
- 申请人： The Board of Regents of the University of Texas System
- 申请人地址： US TX Austin
- 专利权人： The Board of Regents of the University of Texas System
- 当前专利权人： The Board of Regents of the University of Texas System
- 当前专利权人地址： US TX Austin
- 国际申请： PCT/US16/67142 WO 20161216
- 主分类号： C07C50/32
- IPC分类号： C07C50/32 ; C07C311/21 ; C07C233/33 ; C07C225/30 ; C07D295/116 ; C07C233/42 ; C07C233/91 ; C07C311/08 ; A61P35/00
摘要：
Provided herein are naphthoquinones compounds such as those with a hydrogen bond donating group of the formula (I): wherein: R1, R2, R3, R4, R5, and n are as defined herein. Also provided herein are pharmaceutical composition of the present compounds and methods of treatment using the compounds including their use in the treatment of cancer.
公开/授权文献
- US10829427B2 Naphthoquinones, pro-drugs, and methods of use thereof 公开/授权日：2020-11-10
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