- 专利标题: MALT1 INHIBITORS AND USES THEREOF
-
申请号: US15755951申请日: 2016-08-26
-
公开(公告)号: US20190389904A2公开(公告)日: 2019-12-26
- 发明人: Nathanael S. Gray , David A. Scott , John Hatcher , Spandan Chennamadhavuni , Ari M. Melnick , Lorena Fontan Gabas , Hao Wu , Qi Qiao , Guangyan Du
- 申请人: Nathanael S. Gray , David A. Scott , John Hatcher , Spandan Chennamadhavuni , Ari M. Melnick , Lorena Fontan Gabas , Hao Wu , Qi Qiao , Guangyan Du
- 申请人地址: US NY Ithaca US MA Boston US MA Boston
- 专利权人: Cornell University,Dana-Farber Cancer Institute, Inc.,Children's Medical Center Corporation
- 当前专利权人: Cornell University,Dana-Farber Cancer Institute, Inc.,Children's Medical Center Corporation
- 当前专利权人地址: US NY Ithaca US MA Boston US MA Boston
- 国际申请: PCT/US2016/049038 WO 20160826
- 主分类号: C07K5/11
- IPC分类号: C07K5/11 ; A61K38/07
摘要:
Provided herein are compounds of Formula (I) and pharmaceutical compositions thereof, which may be useful as MALT1 inhibitors. Also provided are for the treatment of proliferative disorders (e.g., cancer (e.g., non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, MALT, lymphoma), benign neoplasm, a disease associated with angiogenesis, an autoimmune disease, an inflammatory disease, an autoinflammatory disease) by administering a compound of Formula (I).
公开/授权文献
- US10711036B2 MALT1 inhibitors and uses thereof 公开/授权日:2020-07-14