Invention Application
- Patent Title: AZAINDOLES AS INHIBITORS OF HPK1
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Application No.: US16568459Application Date: 2019-09-12
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Publication No.: US20200000780A1Publication Date: 2020-01-02
- Inventor: Timothy HEFFRON , Sushant MALHOTRA , BinQing WEI , Bryan CHAN , Lewis GAZZARD , Emanuela GANCIA , Michael LAINCHBURY , Andrew MADIN , Eileen SEWARD , Yonghan HU
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Priority: CNPCT/CN2017/076713 20170315
- Main IPC: A61K31/437
- IPC: A61K31/437 ; A61K31/444 ; A61K31/5377 ; C07D471/04 ; A61K31/506 ; A61K31/513
Abstract:
Azaindole compounds and their use as inhibitors of HPK1 are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the azaindole compounds.
Public/Granted literature
- US10952995B2 Azaindoles as inhibitors of HPK1 Public/Granted day:2021-03-23
Information query
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