发明申请
- 专利标题: SCAFFOLD FOR IN VITRO MODELING AND TRANSPLANTATION THERAPY OF PHOTORECEPTORS
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申请号: US16506471申请日: 2019-07-09
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公开(公告)号: US20200010799A1公开(公告)日: 2020-01-09
- 发明人: Zhenqiang Ma , Juhwan Lee , Yei Hwan Jung , Michael Phillips , David Gamm , Shaoqin Gong , Inkyu Lee
- 申请人: Wisconsin Alumni Research Foundation
- 主分类号: C12N5/0793
- IPC分类号: C12N5/0793
摘要:
Photoreceptor scaffolds that can be used for transplantation of organized photoreceptor tissue, with or without retinal pigment epithelial cells, which may improve grafted cell survival, integration, and functional visual rescue are disclosed herein. The scaffolds include a cell support layer having at least one cube-shaped reservoir fluidly connected to a plurality of through-holes and at least one cell in the at least one cube-shaped reservoir.