Invention Application
- Patent Title: METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING HIV
-
Application No.: US16708787Application Date: 2019-12-10
-
Publication No.: US20200101152A1Publication Date: 2020-04-02
- Inventor: Yves LEVY , Gerard ZURAWSKI , Sandra ZURAWSKI , Anne-Laure FLAMAR
- Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale) , Baylor Research Institute , Universite Paris Est Creteil Val De Marne , Assistance Publique Hopitaux de Paris
- Main IPC: A61K39/21
- IPC: A61K39/21 ; A61P31/18 ; C07K14/005 ; C12N7/00 ; C07K16/28 ; C07K16/10 ; A61K39/12
Abstract:
Methods and compositions are provided that can be used to vaccinate against and treat HIV. Specifically contemplated are vaccine compositions and methods of using these compositions treat HIV in patients. Aspects of the disclosure relate to an anti-CD40 antibody-HIV antigen fusion protein comprising (i) an anti-CD40 heavy chain (HCD40)-HIV antigen (Ag) fusion protein comprising the formula: HCD40-Ag, wherein Ag is a polypeptide with at least 80% sequence identity to SEQ ID NO:1; and (ii) an anti-CD40 light chain (LCD40).
Public/Granted literature
- US10722572B2 Methods and compositions for treating and preventing HIV Public/Granted day:2020-07-28
Information query
