- 专利标题: DOPAMINE D2 RECEPTOR LIGANDS
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申请号: US16826028申请日: 2020-03-20
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公开(公告)号: US20210147355A1公开(公告)日: 2021-05-20
- 发明人: Edward Holson , Florence Fevrier Wagner , Michel Weiwer , Edward Scolnick , Michelle Palmer , Luka Dordevic , Michael C. Lewis , Jennifer Q. Pan , Yan-Ling Zhang , Qihong Xu
- 申请人: The Broad Institute, Inc. , Massachusetts Institute of Technology
- 申请人地址: US MA Cambridge; US MA Cambridge
- 专利权人: The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人: The Broad Institute, Inc.,Massachusetts Institute of Technology
- 当前专利权人地址: US MA Cambridge; US MA Cambridge
- 主分类号: C07D207/12
- IPC分类号: C07D207/12 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D405/06 ; C07D413/12 ; C07D417/12 ; C07D451/06 ; C07D471/10 ; C07D491/048 ; C07D491/052 ; C07D491/056 ; C07D491/107 ; C07D211/18 ; C07D211/38 ; C07D211/42 ; C07D211/48 ; C07D211/58 ; C07D211/62 ; C07D211/70 ; C07D211/22 ; A61P25/18 ; A61P25/16
摘要:
The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.
公开/授权文献
- US11498896B2 Dopamine D2 receptor ligands 公开/授权日:2022-11-15
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