- 专利标题: GLYCEROL DERIVATIVE, PREPARATION METHOD THEREFOR, AND IMMUNOMODULATOR COMPRISING SAME AS EFFECTIVE INGREDIENT
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申请号: US17047123申请日: 2019-04-19
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公开(公告)号: US20210198183A1公开(公告)日: 2021-07-01
- 发明人: Ki Young SOHN , Jae Wha KIM , Sun Young YOON , Chang Hyun YOO , Jin Seon JEONG
- 申请人: ENZYCHEM LIFESCIENCES CORPORATION
- 申请人地址: KR Jecheon-si, Chungcheongbuk-do
- 专利权人: ENZYCHEM LIFESCIENCES CORPORATION
- 当前专利权人: ENZYCHEM LIFESCIENCES CORPORATION
- 当前专利权人地址: KR Jecheon-si, Chungcheongbuk-do
- 优先权: KR10-2018-0046890 20180423
- 国际申请: PCT/KR2019/004789 WO 20190419
- 主分类号: C07C233/20
- IPC分类号: C07C233/20 ; C07C233/18 ; C07C233/38 ; C07C327/28 ; C07C235/06 ; C07C69/708 ; A61P37/06
摘要:
Disclosed are a glycerol derivative that is useful for improving, preventing or treating inflammation-related diseases by inhibiting overexpression of various inflammatory cytokines such as IL-4, IL-6 and so on, or chemokine CXCL8 and reducing migration of HL-60 cell lines, preparation method therefor, and an immunomodulator containing the same as active ingredient. It includes a glycerol derivative represented by Chemical formula 2 or 3 in the specification.
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