- 专利标题： SUBSTITUTED GUANIDINO AND AMIDINO REAGENTS AND THE USE THEREOF FOR PROTEIN DENATURATION
-
申请号： US17314748申请日： 2021-05-07
-
公开(公告)号： US20210388022A1公开(公告)日： 2021-12-16
- 发明人: Xiaoxiao Liu , Wenjing Li , Matthew A. Lauber
- 申请人： Waters Technologies Corporation
- 申请人地址： US MA Milford
- 专利权人： Waters Technologies Corporation
- 当前专利权人： Waters Technologies Corporation
- 当前专利权人地址： US MA Milford
- 主分类号： C07K1/113
- IPC分类号： C07K1/113 ; C07C279/04 ; C12Q1/37 ; C07D487/04
摘要：
The present disclosure relates to a system for a composition for protein denaturation. The composition includes a non-nucleophilic denaturant comprising a substituted guanidine, wherein the denaturant has a pKa value greater than about 10, and wherein the concentration of the substituted guanidine is less than 250 mM.
信息查询
