Invention Application
- Patent Title: NANOFIBER REINFORCEMENT OF ATTACHED HYDROGELS
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Application No.: US17365076Application Date: 2021-07-01
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Publication No.: US20220001079A1Publication Date: 2022-01-06
- Inventor: Benjamin J. Wiley , Huayu Tong , Jiacheng Zhao
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Main IPC: A61L27/52
- IPC: A61L27/52 ; A61L27/20 ; A61L24/02 ; A61L27/34 ; A61L27/30 ; A61L27/32 ; A61L27/36

Abstract:
Described herein are hydrogels attached to a base with the strength and fatigue comparable to that of cartilage on bone and methods of forming them. The methods and apparatuses described herein may achieve an attachment strength between a hydrogel and a substrate equivalent to the osteochondral junction. In some examples the hydrogel may be a triple-network hydrogel (such as BC-PVA-PAMPS) that is attached to a porous substrate (e.g., a titanium base) with the shear strength and fatigue strength equivalent to that of the osteochondral junction.
Public/Granted literature
- US11707555B2 Nanofiber reinforcement of attached hydrogels Public/Granted day:2023-07-25
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