An electronic device may include an electronic display including display pixels to display an image based on compensated image data. The electronic display may also include a stressed reference pixel to exhibit burn-in related aging in response to one or more stress sessions and a non-stressed reference pixel configured to not undergo the one or more stress sessions. Additionally, the electronic device may include image processing circuitry to determine a panel-specific aging profile based on a comparison between one or more properties of the stressed reference pixel and the one or more properties of the non-stressed reference pixel. The image processing circuitry may also generate one or more gain maps based on the panel-specific aging profile and generate the compensated image data by applying the one or more gain maps to input image data.