- 专利标题： ANTIHYPERTENSIVE POLYOL COMPOUND AND DERIVATIVE THEREOF
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申请号： US17424105申请日： 2020-06-12
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公开(公告)号： US20220098134A1公开(公告)日： 2022-03-31
- 发明人: Honglin LI , Zhenjiang ZHAO , Rui WANG , Yinchu SHEN , Jianjun FU , Yufang XU , Xuhong QIAN , Qian JIAO , Shiliang LI
- 申请人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- 申请人地址： CN Shanghai
- 专利权人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- 当前专利权人： EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- 当前专利权人地址： CN Shanghai
- 优先权： CN201910507506.4 20190612
- 国际申请： PCT/CN2020/095974 WO 20200612
- 主分类号： C07C33/26
- IPC分类号： C07C33/26 ; C07C43/23 ; C07C49/82 ; C07C33/30 ; C07C69/16 ; A61P9/12
摘要：
The present invention provides a compound as represented by formula I, or a pharmaceutically acceptable salt or ester, a prodrug, an optical isomer, a stereoisomer, or a solvate thereof. The compound provided by the present invention can be used for preparing drugs for preventing or treating hypertension, or hypertension-related diseases, or pulmonary hypertension, or pulmonary hypertension-related diseases. The compound provided by the present invention has a different mechanism from existing drugs for treating hypertension and pulmonary hypertension, thereby laying a new material foundation for the development of drugs for treating hypertension and pulmonary hypertension.
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